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KMID : 0882420100780060737
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Korean Journal of Medicine
2010 Volume.78 No. 6 p.737 ~ p.740
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A case of improved Menetrier’s disease after the eradication of Helicobacter pylori and treatment with a proton pump inhibitor
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Yoon Ji-Hoon
Park Seung-Jei
Choi Jae-Won
Choi Sung-Won
Park Seung-Keun
Park Hee-Ug
Kim Hye-Sook
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Abstract
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Menetrier’s disease is a protein-losing hypertrophic gastropathy characterized by diffuse tremendous thickening of the gastric wall caused by excessive proliferation of the mucosa. Although the cause of Menetrier’s disease is unknown, an association with Helicobacter pylori has been reported. A 42-year-old man was hospitalized for the evaluation of progressive body weight loss and indigestion for 6 months, with recently aggravated epigastric discomfort. Gastroscopy revealed prominent mucosal folds in the body and fundus. The histological findings revealed gastritis with erosions and foveolar hyperplasia. After eradicating the Helicobacter pylori and treatment with a proton pump inhibitor, clinical and endoscopic resolution ensued. (Korean J Med 78:737-740, 2010)
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KEYWORD
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Menetrier’s disease, Helicobacter pylori
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